| Sherbet | A sweet, refreshing drink. |
| Shiavax | A protector of the light. |
| Shift | To change or move position. |
| Shigeo | A man of great prosperity. |
| Shikamaru | A deer in the forest. |
| Shikhir | One who is very radiant. |
| Shilad | A person of stone strength. |
| Shinji | True second son or child. |
| Shogo | A child of bright wisdom. |
| Shohei | To fly and be peaceful. |
| Shoojit | One who is always winning. |
| Shota | A big, thick, or stout boy. |
| Shoto | One who flies and soars. |
| Shrav | One who is attentive to all. |
| Shuka | A Sanskrit name meaning parrot. |
| Siavan | A name meaning a forest dweller. |
| Siavo | A name meaning a bright spirit. |
| Siddharaja | A name meaning perfect king. |
| Signal | A name meaning a clear sign. |
| Sigur | A name meaning victory guard. |
| Sikhandin | One who has a tuft of hair |
| Silicon | A chemical element found in sand |
| Sinatra | A surname meaning from Sinagra |
| Sindh | A region near the Indus River |
| Sindhuveer | A brave warrior of the Indus |
| Sintra | A town of hills and royal palaces |
| Sirocco | A hot Mediterranean wind. |
| Skadi | Norse goddess of the winter. |
| Skadiyo | A variation of winter goddess. |
| Slash | To cut with a sweeping stroke. |
| Snoop | To pry or investigate secretly. |
| Sobek | Ancient Egyptian god of the Nile. |
| Soh | Sine over hypotenuse in math. |
| Sokar | Ancient Egyptian god of the dead. |
| Solar | Relating to the sun or sunlight. |
| Soleus | A muscle located in the lower calf area. |
| Sophos | A Greek term meaning wise or clever. |
| Soul | The spiritual essence of a person. |
| Spand | A variant of the word for expansion. |
| Speck | A tiny spot or a very small particle. |